Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep209 | Reproduction, endocrine disruptors and signalling | ECE2015

The commonly used plasticisers (bisphenols and phthalates) as endocrine disrupting chemicals in healthy women and women with polycystic ovary syndrome

Rutkowska Aleksandra , Konieczna Aleksandra , Wilczewska Kamila , Ciechanowicz Agnieszka , Czernych Radoslaw , Kowalewska-Wlas Agnieszka , Laczmanski Lukasz , Kuliczkowska Justyna , Lenarcik Agnieszka , Trzmiel-Bira Anna , Brona Anna , Kuligowska-Jakubowska Monika , Kot-Wasik Agata , Wasik Andrzej , Milewicz Andrzej , Namiesnik Jacek , Wolska Lidia , Rachon Dominik

Plasticisers such as bisphenol A (BPA), bisphenol S (BPS), and phthalates (PAE) are commonly used in daily life in electronic equipment, cans, plastic food containers, and bottles. These substances can interact with oestrogen receptors as well as androgen receptors and therefore they are called endocrine disrupting chemicals (EDC). The aim of this study was to evaluate serum concentrations of BPA, BPS, and selected PAE in healthy women and women with polycystic ovary syndrome ...

ea0035p511 | Endocrine disruptors | ECE2014

The potential role of bisphenol A in the pathogenesis of polycystic ovary syndrome

Rutkowska Aleksandra , Wilczewska Kamila , Laczmanski Lukasz , Kuliczkowska Justyna , Lenarcik Agnieszka , Trzmiel-Bira Anna , Brona Anna , Kuligowska-Jakubowska Monika , Konieczna Aleksandra , Kot-Wasik Agata , Wasik Andrzej , Milewicz Andrzej , Namiesnik Jacek , Rachon Dominik

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, that lead to infertility, type 2 diabetes and coronary heart disease.Bisphenol A (BPA) is one of the most abundant chemicals produced worldwide and is used as a plasticizer in daily life. Nowadays it is also well know that it can interact with estrogen receptors, androgen receptors and peroxisome proliferator-activated receptors γ (PPARγ). Therefore...

ea0035p787 | Obesity | ECE2014

The association between metabolic syndrome and android fat mass and android to gynoid fat mass ratio- are Classification and Regression Trees models helpful?

Brona Anna , Milewicz Andrzej

The aim of the study was to estimate thresholds of android fat mass and android to gynoid fat mass ratio at which metabolic disorders and blood pressure typical of metabolic syndrome appear. Classification and Regression Trees models were used to estimate these thresholds for glucose, HDL cholesterol, triglycerides and systolic and diastolic blood pressure.Methods: healthy postmenopausal women were recruited for the study. Blood samples were collected fo...

ea0022p802 | Thyroid | ECE2010

Predictors of cardiovascular risk in patients with hyperthyroidism before and after radioiodine therapy

Brona Anna , Milewicz Andrzej , Bohdanowicz-Pawlak Anna , Jedrzejuk Diana , Arkowska Anna

It is suggested that radioiodine therapy in hyperthyroidism can increase mortality because of cardiovascular diseases. To determine that fact we have evaluated how the levels of predictors of the cardiovascular risk in serum such as: glucose, insulin, total cholesterol and high-density cholesterol, low-density cholesterol and triglycerides as well as CRP, fibrinogen and D-dimers changed in hyperthyroidism cases before and 12 up to 16 and 24 up to 28 weeks after radioiodine the...

ea0090ep313 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Is the concentration of ghrelin and leptin important for the course of COVID-19 infection?

Kuliczkowska-Płaksej Justyna , Jawiarczyk-Przybyłowska Aleksandra , Zdrojowy-Wełna Aleksandra , Brona Anna , Bolanowski Marek

Objectives: SARS-Cov2 infection can lead to severe cytokine storm especially in obese patients. It is known that the cytokine storm might lead to severe clinical manifestations or even acute mortality in critically ill patients with COVID-19. Ghrelin as well as leptin can act as the proinflammatory cytokines. The essential question is whether the cytokine storm in COVID-19 patients with obesity is associated with adipokines dysregulation.Aim: The st...